CRS 2026 Annual Meeting
Date: July 7-11, 2026
Location: Lisbon, Portugal
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Learn how sa¹ú¼Ê´«Ã½¹ÙÍøÍøÒ³Èë¿Úis advancing oral drug development and delivery of macromolecules with modified release technology, bioavailability enhancement and scientific innovation. Meet with our experts to see how we can support your next breakthrough to bring better treatment to market and to patients.
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SPEAKING ENGAGEMENTS
Speaker: Karunakar Sukuru (Karu), R.Ph., Ph.D., Global Vice President, Pharma Product Development & Head of Scientific Advisory
Date/Time: Wednesday, July 8 at 9:00am
Title: Breaking the Injection Barrier Using Innovative Technologies for Oral Delivery of Midsize and Macromolecules
Oral delivery of macromolecules such as peptides and proteins remains a major challenge due to enzymatic degradation, poor permeability and instability in the gastrointestinal tract. Despite these barriers, oral administration offers clear advantages in patient convenience, adherence and cost reduction. This presentation explores formulation and delivery strategies used to enhance oral bioavailability of macromolecules, with emphasis on lipid-based formulations, enteric softgels and sublingual/buccal routes. Mechanistic considerations including protection from gastric degradation, promotion of solubilization and modulation of intestinal absorption pathways will be discussed. By aligning molecular properties with appropriate formulation and delivery strategies, oral administration may be achievable for a specific range of peptides and biologics, supporting patient-centric product design and lifecycle differentiation.
ABOUT CATALENT
sa¹ú¼Ê´«Ã½¹ÙÍøÍøÒ³Èë¿Ú. is a leading global contract development and manufacturing organization (CDMO) championing the missions that help people live better and healthier lives. Every product that sa¹ú¼Ê´«Ã½¹ÙÍøÍøÒ³Èë¿Úhelps develop, manufacture and launch reflects its commitment to improve health outcomes around the world through its Patient First approach. sa¹ú¼Ê´«Ã½¹ÙÍøÍøÒ³Èë¿Úprovides unparalleled service to pharma, biotech and consumer health customers, delivering on their missions to transform lives. sa¹ú¼Ê´«Ã½¹ÙÍøÍøÒ³Èë¿Útailors end-to-end solutions to meet customers’ needs in all phases of development and manufacturing. With thousands of scientists and technicians and the latest technology platforms at nearly 40 global sites, sa¹ú¼Ê´«Ã½¹ÙÍøÍøÒ³Èë¿Úsupplies billions of doses of life-enhancing and life-saving treatments for patients annually. For more information, visit www.catalent.com.
